Antral Follicles

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This topic contains 13 replies, has 13 voices, and was last updated by Apple Apple 1 year, 9 months ago.

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  • #164
    Victoria
    Victoria
    Participant

    I had a day 21 scan today and only had 4-6 antra follicles counted. Previously I have had day 2 scans for AFC and have had 8-10 but this time I had it done on day 21 and there was less. In all I have read about when to count AF, it says day 2-5.So my question is – is a day 21 AFC accurate or is it likely that more AF’s would appear by day 2 before stimulation starts?Many thanks for your time

    #230
    Jody
    Jody
    Participant

    A female is born with a liftieme supply of eggs and as she grows these eggs are developed. Post her puberty these follicles develop and are relased on a monthly basis. When the woman reaches menopause this supply is exhausted. An antral follicle is a resting follicle and appears as a small fluid fillied sac which contains the immature egg. These follicles can be measured and counted on cycle days 2, 3 and 5. The antral follicles varies every month. Antral follicle count is rightly done on day 3 of the cycle by a Trans vaginal ultrasound.Initially the ovarian volume of both the ovaries is calculated. Further the number of small antral follicles in both the ovaries is measured. These follicles could vary in size from 2-10 mm. Normal AFC is a bit variable in different centres. It is roughly considered to be about 3-8 per ovary. AFC count is a major predictor of the ovarian reserve and could reflect the size of the remaining primordial follicle pool. Low fertility is characterized by low numbers of oocytes and are usually associated with high follicle stimulating hormone levels (FSH).

    #233
    Alice
    Alice
    Participant

    Normal AFC is a bit variable in different centres. It is roughly considered to be about 3-8 per ovary. AFC count is a major predictor of the ovarian reserve and could reflect the size of the remaining primordial follicle pool.Low fertility is characterized by low numbers of oocytes and are usually associated with high follicle stimulating hormone levels (FSH).It is considered to be more accurate than the basal FSH testing for older women >44 years of age when predicting IVF outcome. When an average to high number of antral follicles (eight or more) are visible on the ultrasound, fertility specialists expect to be able to retrieve a good number of eggs and the pregnancy rates are higher than average. If few antral follicles appear, a poorer response is expected and the IVF cycle could be cancelled to try for better results the following month.

    #271
    Jody
    Jody
    Participant

    A low AFC is a major factor in the diagnosis of poor ovarian reserve, that is, low fertility characterized by low numbers of remaining oocytes in the ovaries, usually accompanied by high follicle stimulating hormone (FSH) levels. Several studies show that an AFC test is more accurate than basal FSH testing for older women (< 44 years of age) in predicting IVF outcome. However, it does not appear to add any predictive information about success rates of an already established pregnancy after IVF. It is also a major determinant of the success of ovarian hyperstimulation. It has been suggested that counting the antral follicles measuring 2–5 or 4–6 mm in diameter is preferable. On the other hand, the number of smaller antral follicles (2–5 mm) is highly correlated with the total number of antral follicles (2–10 mm), and therefore it is suggested that counting all identifiable antral follicles of 2–10 mm in diameter would provide the most practical method for assessment of AFC in clinical practice. Three-dimensional (3D) automated follicular tracking is a developing technique that can substantially decrease both intra- and inter-observer variability in estimating the AFC.

    #276
    Kate
    Kate
    Participant

    The number of antral follicles visible on ultrasound is indicative of the number of microscopic (and sound asleep) primordial follicles remaining in the ovary. Each primordial follicle contains an immature egg that can potentially develop and ovulate in the future.When there are only a few antral follicles visible, there are far fewer eggs remaining as compared to when there are more antrals. As women age, they have less eggs (primordial follicles) remaining and they have fewer antral follicles.Antral follicle counts are a good predictor of the number of mature follicles that we will be able to stimulate in the woman’s ovaries when we give injectable FSH medications that are used for in vitro fertilization. The number of eggs retrieved correlates with IVF success rates.

    #312
    Milka
    Milka
    Participant

    An antral (resting) follicle is a small, fluid-filled sac that contains an immature egg. The follicles can be seen, measured and counted on Cycle Days 2, 3, and 5 by using ultrasound. The number of antral follicles varies from month to month.The Basal Antral Follicle Count, along with the woman’s age and Cycle Day 3 hormone levels, are used as indicators for estimating ovarian reserve and the woman’s chances for pregnancy with in vitro fertilization. In other words, the antral follicles are a good predictor of the number of mature (dominant) follicles in a woman’s ovaries that can be stimulated by medications leading up to IVF. The number of eggs retrieved correlates directly with IVF success rates.

    #326
    Molly
    Molly
    Participant

    The number of follicles, each containing one egg, which is available in the ovarian pool relates to the chance of success of in vitro fertilization (IVF). These numbers decline with age and in some women they decline abnormally rapidly. For couples who are trying to conceive and their care givers, methods of predicting the potential outcome of IVF can be important in making medical decisions for couples who are trying to conceive.One important tool for measuring the ovarian pool is in fact a direct measure of the follicles as they emerge in a given month.It is the ultrasound observation of the number of small follicles in the ovary during a menstrual period. At this point there are no large follicles and the pool of follicles which will emerge that month is beginning to grow. As the fluid accumulates, even a few milliliters (a teaspoonful is 5 ml) of fluid in the antral follicle can produce a measurable echo on the highly sensitive ultrasound machines used for transvaginal evaluation of the ovaries. These machines are expensive but they are worth it for this test. Follicles between 2 and 5 mm can be visualized and counted. The antral follicle count or AFC must be done when the follicles have not begun to grow. Thus it is scheduled day 2, 3 or 4 of the cycle prior to considering IUI or IVF therapy. Because there is not a huge variation in follicles from month to month, this test can give a good idea of the prognosis for the future. It is a good indicator of the number of follicles and thus eggs which can be responsive to stimulation.

    • This reply was modified 2 years, 7 months ago by Molly Molly.
    #406
    Monica
    Monica
    Participant

    The antral follicle count is a fairly simple test to perform with high quality ultrasound equipment. It allows us to evaluate a woman’s ovarian reserve – her supply of eggs for the future. Tests of ovarian reserve do not measure the quality of the eggs, they only measure the quantity.Egg quality is mostly an age related issue. Quantity is something that we can test with “ovarian reserve tests”. Most fertility doctors in the US rely on 3 ovarian reserve tests to evaluate their patients.By counting the number of antral follicles we can learn about the quality of eggs remaining. We also can learn about the expected response to ovarian stimulation drugs and we can predict chances for successful in vitro fertilization treatment.

    #473
    Bridget
    Bridget
    Participant

    Antral count is just ONE indicator of low ovarian reserve…there are several more factors (such as FSH, estradiol and those #s again after stim meds) that most REs look at. REs also look at a trend…in my case, my antral is consistently low, my FSH is high, and I don’t respond well to stim meds. Thus my RE has recommended IVF with donor eggs. Can I still have my own baby naturally or thru IUI w/stims? Of course! Are the chances good? No. They’re terrible.What I’m sayin in this: you just have one piece to the puzzle, so don’t jump ship and think all is lost. You still need to get more info, and possibly go thru several stim cycles before you know if you have DOR/LOR.Also keep in mind that blondewifey and Pink_Green are EXCEPTIONS to the rule. They are two of the lucky ones that beat the odds. Their stories are wonderful, and we all hope to have similar stories, but MOST of the time women with issues such as DOR don’t get as lucky and have to face the decision of no baby or IVF. It’s reality and it sucks, but…YOU ARE NOT THERE YET.Best of luck to you darlin!!!

    • This reply was modified 2 years, 6 months ago by Bridget Bridget.
    #617
    Sarah
    Sarah
    Participant

    The antral follicles count (AFC) is performed by a fairly sophisticated ultrasound technique that joins the previous evaluation of what might be called “ovarian age”, because ovarian reserve is also an expression of aging.
    With a transvaginal ultrasound probe (preferably a three-dimensional type) will be conducted a volumetric assessment of ovaries and then will proceed to the counting of antral follicles (2-10mm) 3-5 in the early follicular phase of the cycle; particularly the counting of follicles with a diameter between 2 and 6mm (small antral follicles) seems to correlate better with the functional ovarian reserve.

    #643

    Daria
    Participant

    This follicles that have a size of not more than 8 mm, and are counted in the ovaries by ultrasound transvaginal ultrasound. This way of establishing their number is considered to be the most reliable. The number of antral follicles is identical to how much in the ovaries is of primordial follicles. The latter are the precursors of the egg itself. Therefore, the study described avoids microscopic analysis of ovaries. As a result of counting the antral follicles in the ovaries can be accurately set the ovarian reserve of women, namely, the number of her eggs, which is ready for immediate fertilization.

    #693
    Ana
    Ana
    Participant

    although i may not help you with this topi c a lot because i am not familiar with it very good but i will tell you what i know. the number of antral follicles visible on ultrasound is indicative of the number of microscopic primordial follicles remaining in the ovary. Each primordial follicle contains an immature egg that can potentially develop and ovulate in the future.when there are only a few antral follicles visible, there are far fewer eggs remaining as compared to when there are more antrals. if you want to know more then i think that you have to ask your doctor.

    #738

    Donna
    Participant

    Primordial germ cells develop in the yolk sac and migrate to gonadal folds to the 7th week of gestation. In the process of migration oogonia divide by mitosis and reach the maximum number of 6-7mln to 20 weeks of gestation. Already from the middle of pregnancy the number of oogonia begins to decline rapidly. Entry oogonia in the first stage of meiosis begins with 11-12 weeks of gestation and continues throughout fetal period, this process is characterized by the appearance of a primary oocyte. Furthermore, starting from 20 weeks of gestation starts around each oocyte pregranuleznyh formation of one row of cells, forming a primordial follicle.

    #822
    Apple
    Apple
    Participant

    Antral follicle count is rightly done on day 3 of the cycle by a Trans vaginal ultrasound.Initially the ovarian volume of both the ovaries is calculated. Further the number of small antral follicles in both the ovaries is measured.
    These follicles could vary in size from 2-10 mm. Normal AFC is a bit variable in different centres. It is roughly considered to be about 3-8 per ovary. AFC count is a major predictor of the ovarian reserve and could reflect the size of the remaining primordial follicle pool. Low fertility is characterized by low numbers of oocytes and are usually associated with high follicle stimulating hormone levels .

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